BIOMS – Gesellschaft Für Bioanalytik Münster EV
The association Bioanalytik Münster e. V. (bioanalytik-muenster) was founded by local companies, the city of Muenster, local banks, the two Muenster universities, and other local development organisations such as the Chamber of Commerce in November 2000.
It serves as a central communication and information agency for companies, investors, researcher institutions and public authorities to develop and implement the regional development strategy in RTD and economic exploitation of nanobioanalytics
IBE R&D gGmbH Institute for Lung Health offers services for the toxicological evaluation of micro- and nanoparticles. In addition, IBE gGmbH has developed new analytical methods to evaluate the effect and impact of nanoparticles on several tissues including lung tissue by using alveolar macrophages. To detect nanoparticles in tissue, IBE uses its expertise in hyperspectral microscopy, e.g. with the goal to identify regions of interests for further physical analytical methods. These new methods are pathbreaking for the characterisation and quantification of nanoparticles in tissue samples. IBE gGmbH works continuously on new methods to supplement and replace animal testing in the biomedical evaluation of nanoparticles.IBE is partner in several german reference projects as NanoCare, NanoBioDetect, NanoGem and ZEBET.
Tascon GmbH offers analytical services and consulting in the area of surface analysis. In addition to the three focus techniques ToF-SIMS (Time-of-Flight Secondary Ion Mass Spectrometry), XPS (X-Ray Photoelectron Spectroscopy) and LEIS (Low Energy Ion Scattering), the complete spectrum of surface analytical methods is covered.Founded in 1997 Tascon GmbH addresses industries in the fields of pharmacy, health care, semiconductors, automotive, coatings, glass, and chemistry. Tascon is accredited as a ToF-SIMS and XPS test laboratory according to DIN EN ISO/IEC 17025. Tascon’s success builds both on state-of-the-art instrumentation as well as highly qualified staff from the fields of physics, chemistry, biology, biochemistry and geology. Tascon GmbH has been engaged in the ToF-SIMS analysis of organic and biological materials for several years now.
The Biomedical Technology Centre (BMTZ) is a new unit of the Medical Faculty Muenster for the development and evaluation of novel technologies in biomedical applications. The work is supported by the membership as a core group in the new Nanobioanalytics Centre Muenster (NBZ) a joint initiative of Wirtschaftsförderung Münster, analytical SME and the Medical faculty. The research interests focus on the application of nanotechnologies and the development of biophotonic technologies as Digital Holography, midIR spectroscopy, flow cytometry and OCT. The second research interest is the development of methods and technologies for nanomaterials toxicology assessment and the characterisation of nanomaterials biological effects.
OxProtect GmbH The research focus of the OxProtect GmbH is to examine the influence of materials/nanomaterials, different reagents or drugs, and agonists and antagonists on the activation status or the functional capacity of blood cells (platelets, monocytes, granulocytes, t-cells), but also endothelial cells and joint cells. The function of the cells as well as the changes or activity can be analysed by flow cytometry, aggregation assays, adhesion assays or ELISA assays.Not only human cell function testing but also animal cell function testing is established in the OxProtect GmbH, for example for mouse, rat, rabbit, sheep, or many other animal species cells. On these cells we can examine for example antibody binding, antigen binding, morphology, cell associate formation and cell fragmentation.OxProtect moreover offers new developed analytical methods in the area of misfolded proteins, which among other things are built after contact with materials/nanomaterials. These misfolded proteins play a pivotal role in blood coagulation and inflammation. For protein qualification and quantification with special tools we use techniques like SDS-PAGE, 2D electrophoresis, and Western Blot analysis, for cell analysis approved and new developed immunocytochemic assays.